The sole Late Medieval work in the treasury is the silver gilded chalice, with the date 1510 on the stem. This bautiful masterpiece was donated to Loreto Treasure by Christoph Ferdinand Popel Count of Lobkowicz in 1654.

Silver gilded Chalice is decorated with a combined technique; judging by the formal arrangement and the selection of saints used in the decoration, it is most likely a Bohemian - Prague work. The basket (the actual body of the vessel) has six fields of alternately blue and red enamel with linear half-figures of the saints, Suffering Christ and the Virgin Mary; on the six-lobed base there are relief, cast and finely chased half-figures.